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Microdosing for Beginners

Last updated on August 22nd, 2023

What is Micro-dosing?

Micro-dosing involves taking a tiny dose of psychedelic hallucinogens or other drugs. Most popularly, people use magic mushrooms (psilocybin) or LSD (acid), but you could potentially micro-dose on any substance. When taking a micro-dose, you should not experience sensory or cognitive distortion. If you do, decrease the dose!

What are the benefits of micro-dosing?

Most data collected indicating potential health benefits of micro-dosing were collected through self-reporting, which is not the most reliable way. However, more and more studies are investigating their direct effect. Another issue, is that we don’t really know the long-term effects of micro-dosing.

A study in Harm Reduction Journal categorized several possible benefits from reports by microdosers. These benefits include:

  1. Improved focus, concentration, and mindfulness
  2. Improved energy, wakefulness, and stimulation
  3. Cognitive benefits, such as enhanced problem solving
  4. Social benefits
  5. Reduced anxiety
  6. Creativity
  7. Reduced symptoms, such as stress
  8. Improved mood, optimism, and life appreciation
  9. Improved body functioning
  10. Self-efficacy, including improved ambition, productivity, and motivation

Microdosing Protocols

There are different protocols that can help guide you through this journey. All of them include a resting period of 2-4 weeks after finishing a cycle of 4-8 weeks of micro-dosing. This is an essential step to avoid building tolerance and maintain the beneficial effects.

  1. Fadiman Protocol
  2. Micro-dosing Institute Protocol
  3. MDI
  4. Stamet’s Protocol
  5. Nightcap Protocol
  6. Intuitive micro-dosing

James Fadiman’s Protocol

The most well-known micro-dosing protocol is named after Dr. James Fadiman. He created this protocol to observe the effects of micro-dosing by clearly distinguishing between micro-dosing days and non-microdosing days.


  • DAY 1: 1st micro-dosing day
  • DAY 2: transition day (after glow effect)
  • DAY 3: normal day
  • DAY 4: 2nd micro-dosing day

CYCLE: Continue this cycle for four to eight weeks
RESET: Two to four weeks of rest

Micro-dosing recommendations:

  • Be conservative when it comes about dosage and days between doses. Dr. Fadiman recommends something like one-tenth of a normal dose. For LSD, a normal dose could be between 100-120 micrograms (mcg), so a micro-dose should be between 6 and 12 mcg. However, you are your own expert, listen to your body!
  • Follow your nomal patters: make sure you eat as normal, drink water, take your medication, have restful sleep, and any normal activity you follow.
  • Be discreet about who you tell about your experience.
  • Test your substance! No benefit will come from a laced substance.

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